Off Label Drug Promotion…Coming Soon?

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(I want to thank my friend and colleague Jeff Karr, DPM (www.osteomyelitiscenter.com) for alerting me to this news story.) Just this past week the U.S. Second Circuit Court of Appeals ruled to prohibit criminal prosecution for truthful off label promotion of drugs as a First Amendment right. An excellent analysis of the case can by … Read more

What’s New & Interesting in the Infectious Diseases Literature – Summer 2012

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I confess…I have been a bit lackadaisical in my scanning through the journals I receive each month.  This point was driven home to me yesterday when I went to find room on my desk to put some work and realized it was totally covered with stacks of journal back issues I had put aside with … Read more

Radio Interview About Diabetic Foot Infections and SALSAL

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This past Sunday, July 15, I had the pleasure of participating in a radio interview on WOKV, Jacksonville, FL, the largest, most listened to talk radio station in Northern Florida. Here is the link to the audiostream: http://wokv.media.streamtheworld.com/audio/save_leg_save_101730761.mp3 The show was hosted by Desmond Bell, DPM.  Des, a former student “done good”, is the Executive … Read more

A New Review of Antibiotic Therapy for Osteomyelitis

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I wish all of my readers a healthy, happy and prosperous 2012.  With this post I am trying something a bit different.  In the past I usually waited to put up a post until I come up with an “ah ha” moment on something I have seen, heard or read about which I then pontificate … Read more

Literature Update – Antimicrobial Agents and Chemotherapy, Sept, 2011

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As I have mentioned in a previous post there are a number of journals I follow to stay abreast of developments in the ID, microbiology and antibiotic world.  For updates on the latest in antibiotic development from pre-clinical through clinical testing no journal beats the American Society of Microbiology’s Antimicrobial Agents and Chemotherapy (http://asm.org/).  Just … Read more

“PSEUDOMONA-PHOBIA”

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For a number of years I have referred in my lectures to the word I have termed “Pseudomonaphobia”.  Basically, this is an irrational fear of the organism Pseudomonas aeruginosa (PA) when isolated from a culture of a wound in the foot.  I really believe that this arises in most Podiatrists during the residency interview process … Read more

The Attack of the MDROs (ESBL, KPC, NDM-1, NDM-2)

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I just returned from the DFCON meeting in Los Angeles, always my favorite scientific conferences of the year (I have blogged about it previously https://www.leinfections.com/diabetic-foot/the-olmos-award-and-dfcon-2010/).  My topic this year was “Drugs and Bugs 2011”.  Since I gave a similar talk last year I had to try to find a few “hot” topics to update the … Read more

Cultures, Antibiotics and Osteomyelitis

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I received this question from a reader: In suspected osteomyelitis do you stop antibiotics prior to obtaining a bone culture? For how long? This comment came in under my entry on the VULCAN trial but I actually covered the question in a post almost exactly a year ago.  I am reprinting my response here for … Read more