Literature Update – Antimicrobial Agents and Chemotherapy, Sept, 2011

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As I have mentioned in a previous post there are a number of journals I follow to stay abreast of developments in the ID, microbiology and antibiotic world.  For updates on the latest in antibiotic development from pre-clinical through clinical testing no journal beats the American Society of Microbiology’s Antimicrobial Agents and Chemotherapy (http://asm.org/).  Just … Read more

Why I Don’t Eat Raw Oysters

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The more I read the infectious disease literature the more my diet becomes limited. It seems that new reports of contaminated food are published regularly.  It gets to a point where you don’t know what you should and should not eat!  I have always been wary of raw foods and rarely eat sushi especially after … Read more

“PSEUDOMONA-PHOBIA”

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For a number of years I have referred in my lectures to the word I have termed “Pseudomonaphobia”.  Basically, this is an irrational fear of the organism Pseudomonas aeruginosa (PA) when isolated from a culture of a wound in the foot.  I really believe that this arises in most Podiatrists during the residency interview process … Read more

More on Antibiotics and Osteomyelitis

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I have blogged a number of times about the questions surrounding some of the unknown, unproven issues surrounding the treatment of osteomyelitis including duration of antibiotic therapy and the “need” for surgical debridement. It continues to amaze me how it does not matter where, or to whom I lecture, if I ask the question “How … Read more

The Attack of the MDROs (ESBL, KPC, NDM-1, NDM-2)

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I just returned from the DFCON meeting in Los Angeles, always my favorite scientific conferences of the year (I have blogged about it previously https://www.leinfections.com/diabetic-foot/the-olmos-award-and-dfcon-2010/).  My topic this year was “Drugs and Bugs 2011”.  Since I gave a similar talk last year I had to try to find a few “hot” topics to update the … Read more

THE 80% SOLUTION (With apologies to Sir Arthur Conan Doyle)

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This Tuesday, February 22, I was quoted in a very fair and balanced article in the Wall Street Journal by Science Reporter Laura Johannes dealing with laser treatment of onychomycosis. During my interview with Ms. Johannes I bemoaned the lack of published evidence, not only for laser therapy of onychomycosis, but for any of the … Read more

WHEN AN “INFECTION” IS NOT AN INFECTION

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I know that sometimes my posts can be a bit esoteric discussing the minutia of antibiotic dosing, findings in the literature, etc.  So, to change gears a bit, I would like to make this a rather basic clinical discussion.  I know that some of you may find this too simplistic but given the number of … Read more