One of the trickiest issues in prescribing linezolid for patients with MRSA or VRE infections is the potential for a drug-drug interaction, leading to serotonin syndrome (SS), with various serotonergic psychiatric medications. It seems that every pharmacy computer system in …
Read more →As I have mentioned in a previous post there are a number of journals I follow to stay abreast of developments in the ID, microbiology and antibiotic world. For updates on the latest in antibiotic development from pre-clinical through clinical …
Read more →For a number of years I have referred in my lectures to the word I have termed “Pseudomonaphobia”. Basically, this is an irrational fear of the organism Pseudomonas aeruginosa (PA) when isolated from a culture of a wound in the …
Read more →With this entry onto the blog I am trying something new. The IT team at Data Trace has been working on a way to post a PowerPoint slide show to the blog. We believe it is now ready to go. …
Read more →I just returned from the DFCON meeting in Los Angeles, always my favorite scientific conferences of the year (I have blogged about it previously https://www.leinfections.com/diabetic-foot/the-olmos-award-and-dfcon-2010/). My topic this year was “Drugs and Bugs 2011”. Since I gave a similar talk …
Read more →For part 2 of this posting on the new Infectious Diseases Society of America (IDSA) MRSA Guidelines I would like to comment on some of the Executive Summary points made about MRSA bone and joint infections and also vancomycin dosing …
Read more →I received this question from a reader: In suspected osteomyelitis do you stop antibiotics prior to obtaining a bone culture? For how long? This comment came in under my entry on the VULCAN trial but I actually covered the question …
Read more →Well, as I expected and predicted in my previous post, the FDA did not waste much time approving ceftaroline (trade name – Teflaro) for complicated skin and skin structure infections (cSSSI). http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm231594.htm (thanks to Lee Rogers, DPM for forwarding me …
Read more →For a number of years it was widely felt that the first of the new so-called “5th Generation”, or anti-MRSA cephalosporins would be ceftobiprole. This drug, a joint venture by the Swiss company Basilea and Johnson & Johnson had come …
Read more →There is a small group of us that, when we find an interesting article dealing with infections, we pass them on so we can all be stay up to date. Some of the journals are fairly obscure and are not …
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